It is important in poker to consider what two cards opponents in the hand might be holding. But is there a way to consider what cards others might have folded. For example if you are in the blinds with 22 and it gets folded all the way round to you. Can you assume that the likelyhood is that other players folded at least one, if not both of the twos left in the deck?
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Yeah I guess. The only time I really think about this is if I have a middle pocket pair in a spot where there's a raise and a call. Then a tightish player mulls over their hand for awhile then folds, I can pretty much discount two paint cards or an A from the deck going to the flop.