ANOTHER vaccine breakthrough as study confirms Oxford's Covid jab is 'safe and provokes a robust immune response' in over-60s
Oxford University scientists published results from their second phase of testing the coronavirus vaccine, of which Britain has pre-ordered 100million doses, confirming 'positive' progress. The researchers said in a paper published in The Lancet that the jab appears to trigger a 'robust' immune system response in people of all ages and is well tolerated and safe. The team say they will be able to announce within weeks how well the vaccine, being manufactured by UK pharmaceutical firm AstraZeneca, works at protecting people from Covid-19. It comes as vaccine projects by Moderna (pictured bottom right) and Pfizer and BioNTech (bottom left) this week revealed their jabs were 94.5 and 95 per cent effective at preventing Covid-19, respectively, in large studies.
Covid: Will there be more than one coronavirus vaccine?
Successful trials of Covid-19 vaccines by Moderna and a partnership between Pfizer and BioNtech have been announced.
And the Oxford coronavirus vaccine has shown an "encouraging" immune response in adults in their 60s and 70s.
Others are in development, while a third major trial - from Belgian company Janssen - is under way in the UK.
Why do we need a vaccine? If you want your life to get back to normal, then we need a vaccine.
Even now, the vast majority of people are still vulnerable to coronavirus infection. It's only the restrictions on our lives that are preventing more people from dying.
But a vaccine would safely teach our bodies to fight the infection. It would either stop us catching coronavirus in the first place or at least make Covid less deadly.
Having a vaccine, alongside better treatments, is "the" exit strategy.
Which vaccines look most likely to succeed? Pfizer/BioNtech is the first pharmaceutical company to share information from the final stages of vaccine testing.
The data suggests the jab could prevent more than 90% of people from getting Covid-19.
About 43,000 people have been given the vaccine, and no safety concerns have been raised.
Who will get the vaccine first and when can you have it? Moderna ran a trial of its vaccine on 30,000 people in the US, in which half were given dummy injections,
It says its vaccine protects 94.5% of people, after only five of the first 95 trial participants who developed Covid symptoms had received the real vaccine.
Trial results from the vaccine being developed by British drug manufacturer AstraZeneca and scientists at the University of Oxford have been called "encouraging". A strong immune response was seen in adults in their 60s and 70s
The team is now staging bigger trials to see if the vaccine stops people developing Covid.
Meanwhile promising data on a Russian vaccine called Sputnik V has also been released.
Based on interim results from a phase 3 trial, the same stage reached by the Pfizer jab, Russian researchers report that it is 92% efficient.
What still needs to be done? Trials must show the vaccine is safe Clinical trials must show vaccines stop people getting sick or at least reduce the number who die Huge-scale development needs to happen for the billions of potential doses Regulators must approve the vaccine before it can be given It is thought that 60-70% of the global population must be immune to stop the virus spreading easily (known as herd immunity) - billions of people, even if the vaccine works perfectly.
Hallelujah a vaccine! Or two or three or ten. The one with the frothy top looks nice. I can see by your questions that you’re nearly hysterical and in total befuddlement. So, maybe I’ll go easy on you. Nah. I may waiver from the thread title, but I can’t be ars ed to go from thread to thread. In any case , it’s just a thread. Btw,is it about 400 threads in the last six months? In order to encourage debate? You’d be better off sending the odd PM to your buds, as as you’re not pulling in any new punters. Were you in sales? Do you know your market? You need to smarten up your act. Anyway, on to buisness.
Well done you, a flu jab that covers three strains. Let’s hope their guess work is correct, and there are not more strains. Actually I have seen info that links last years flu jab to folks that caught this particular virus early, and the outcome wasn’t good.Ill save that though,wouldn’t want to make anybody edgy. I’m going to cover some ground here, so stay alert if poss. A bit off scrolling to finish with as well😱
The strain in Asia was the milder version,but it’s possible that our super duper deadly strain has made it back there. So originally you had a milder strain circulating in a relatively healthy population. Unfortunately, the western countries let themselves down on that front. See below. The west have far more soft targets. If anybody thinks lovely,I’ve had my vaccine,let’s queue up outside Greggs, then they are missing the point. Good luck to them. Here we find out why there is probably so many excess deaths. Unhealthy folks lounging about at home,heart attacks, dvt , worry and stress etc. You really do need to look at the world picture to get a handle on what’s going on. We are supposedly the fifth richest countries in the world, but healthwise , oh dear. Somebody said they see Geoff Hurst. My mates sister does work for him,basically putting what he wants to say with the correct grammar and punctuation and other stuff with websites. The point is, he’s in his seventies, and does still go to the gym ( when it was open) but can now be seen in his local park, doing a bit. So there’s no excuse if age is what puts folks off. There’s no point in whinging you’re vulnerable,when it’s self inflicted.
You’re gonna like this next bit, not a lot. These Covid deniers, of course they’re not. They’ve all had colds and flu in the past. This virus is so similar to pneumonia,but can multiply much faster, so it can obviously be worse for some folks, with the more severe strain. It’s debatable on what the death rate is, the WHO thinks it’s 0.6%, that’s obviously still a lot of deaths worldwide. The deniers are simply pointing out that it’s not as deadly as it’s made out, stats back that up, for all to see. Attention seekers mainly, but I can’t blame them regarding the trashing of our economy. Time will tell, you’ll see. I’m not bothered by the death numbers going up, that’s a given over the next few most under normal conditions. As for taking a vaccine, it’s ones own choice, as it should always be. This virus isn’t the Black Death,and so few proportionately will die. People die, 500k a year.What’s all the jaw dropping about, when that number dies per year? Of course, the media. In a pandemic, wouldn’t you expect a few more? Does young HAYSIE expect nobody to die at all until a vaccine or two is rolled out? Dream on. Flu still kills the elderly and others,whether they’ve had a vaccine or not, that’s fact. So I wonder why the uptake of the yearly vaccine is indeed not as high as you might think. It’s even lower in other countries. See below. Merkel thinks Germany could have up to 40% of the German population in the vulnerable group. Too much good living, **** e diets. There could be a price to pay.
You seem to think everybody worldwide will in some way be ordered to take vaccines? Is that because countries have put orders in? Don’t hold your breath on that one. Just start a newspaper thread if you want to believe all you here.
You have completely lost the plot.
How disappointing. Are you not coming out to play today?
No all the COVID deniers and anti-vaxxers should be made to sign a legal document stating that in the event of them contracting COVID they are not entitled to any medical treatment,lets see how many of them believe their own bullshot then.
No all the COVID deniers and anti-vaxxers should be made to sign a legal document stating that in the event of them contracting COVID they are not entitled to any medical treatment,lets see how many of them believe their own bullshot then.
There was an article about providing those that have been vaccinated with a QR code, and allowing them to attend football marches. This is an interesting idea, as you could insist on a QR code for doing just about anything, from going to work, or a pub, restaurant, using public transport, taxis, etc. That would change a few minds. The anti-vaxxers would soon get fed up of staying in, while everyone else was pretty much back to normal.
So it’s known that 350,000 elderly die each year. Which is an average of 29,000 per month. But the real rate will be higher during the winter/ flu months. So a vaccine may be rolled out during a period when elderly deaths will be guaranteed to be high? I’d have thought the roll out would be better tested in a slightly younger group, that probably will see far less expected deaths.
Vaccine administered. 50 k elderly deaths in Jan. Media, was it tested for long enough, rushed through? Did the person prove positive for Covid? Ah, no, not now. Natural causes.
Coronavirus vaccines WILL roll out next month: Matt Hancock says UK regulator is already assessing Pfizer's jab and he hopes ALL age groups will start getting it by the end of January as UK deaths pass 70,000 - but numbers show the second wave HAS peaked
The Health Secretary said in a TV briefing today that the Government has officially asked the UK drugs regulator, the MHRA, to consider licensing Pfizer's vaccine, which a report this week revealed to be 95 per cent effective at preventing Covid-19 in a clinical study. Mr Hancock said the NHS was preparing to start giving out vaccines from December but that 'the bulk' of immunisations would be done in the new year. The £15-a-dose jab, co-created by German firm BioNTech, is currently the odds-on favourite to be approved first by the MHRA, although candidates from Moderna and Oxford University are close behind. Professor Jonathan Van-Tam, deputy medical officer for England, said approval would 'happen at the speed of science'.
No insults from me. I’m just curious as to how you see this
You accept that Coronavjrus is deadly and has killed many thousands of people? Assuming you do agree with this then why would a vaccine that could save many thousands of lives not be a good thing?
Surely even if it is a very small % of people, as you state, who actually succumb to Covid would it not be marvellous that we could now save them?
Ah, finally somebody without an agenda. It’s common knowledge that there are different strains of this virus, all of which will potentially have a different affect on different individuals. This all adds up to finding a vaccine that is suitable to treat all age groups and different states of health , near impossible. The media states the world needs billions of doses, why? Have the graveyards and crems been full of kids? 8 out of 10 that test positive have no symptoms, as their immune system have won the battle before it even started. You look at the worldometer charts, which can be confusing, but not when you search for the health stats and care systems for individual countries. It’s not just the “ standard” vulnerable that get hit. Some of those countries have bad diets and heavy drinkers to blame for their counts. Russia, Poland, Ukraine etc. I would focus more on the health aspect than a vaccine, prevention. So back to the vaccine. The elderly are the ones that are the coming off worse, by far.It’s also common knowledge that the elderly can easily get pneumonia after influenza. So why are big Pharma looking for a magic bullet for this virus, when the annual flu jab has about a 50% success rate? Who is responsible for the deaths in previous years for a poor performing vaccine? There are obviously going to be several vaccines, so who decides which one to go with? Nobody will know if they are any good for a couple of years imo. So when you look back, how many lives are going to be saved? Answer. You won’t know. If you believe the numbers ( which I don’t) this virus is still sitting very low on the causes of death this year. Something needs to change regarding the elderly populations health imo. Better diets, more exercise where possible. Spend money and research on that. I’ve worked in several care homes over the years. Same old routine,get them washed and dressed, then fed, then sit them down for hours on end. No wonder their immune systems are poor.( not as a care worker) Trying to find ways to improve the immune system of the elderly in the future is more important than vaccines imo.
Let’s see if all the pneumonia and influenza cases get mixed together with the Covid numbers this winter. I can answer that, you won’t know. So all in all,you won’t know what small % are saved by a vaccine(s) to fight another day. “ A good thing”? You won’t know. In fact, with so many elderly having so many different illnesses,you won’t even know if it was the vaccine that killed them. If it’s a bad winter for flu,then you won’t be able to make head nor tail of any of the numbers.
Trials for AstraZeneca's new 'antibody cocktail' treatment will begin in the UK - and it could prevent Covid-19 for up to a YEAR Manchester participant will be the first in the world to receive 'antibody cocktail' Clinical trial will recruit 5,000 people, including 1,000 from nine sites in the UK Government has signed a deal to secure one million doses if the trial is a success
Kate Bingham, chairwoman of the UK's Vaccine Taskforce, said: 'This is part of the portfolio to protect the whole UK.
'So, obviously, vaccines work in people who have a functional immune system.
'[But] if you are immuno-suppressed and you are going through bone marrow transplants, or indications or treatments that actually reduce your ability to mount an immune response, then this is basically the only current way of providing that short-term passive immunity.
'So we are absolutely looking to protect those people who are immuno-suppressed or those people who need immediate protection, because you will remember that vaccines typically take about six weeks to work.'
The gloom is lifting, now let's get going! 'Professor Positive' KAROL SIKORA says for once the vaccines really are 'game changers' and the 'old normal' is within touching distance
Professor KAROL SIKORA celebrates positive coronavirus vaccine news from Pfizer, Moderna and AstraZeneca, saying the 'whole Covid landscape has been transformed.'
No one should be forced to have the vaccine, but there is nothing to fear from getting it, writes Professor BRENDAN WREN
PROF BRENDAN WREN: Once an immunisation programme is fully under way early next year, society really can begin to return to normal, thanks to the work of scientists across the globe.
So what? And amplified by the media. Politicians lie, remember 💡
Two of them were Tories.
So nobody will be allowed to move around the world without notification of having had a jab? And you rubbish Vespas conspiracy thread?
UK's Covid vaccine minister suggests bars, cinemas and football stadiums could BAN Brits who haven't had jab as he admits No10 is looking at 'immunity passports' Baroness Dido Harding told NHS bosses her team was 'looking at' the plans They have been touted as a way to get swathes of society 'back to normal' Travel companies signalled their support, saying it could kick-start the industry
Nadhim Zahawi MP warned businesses may start requiring proof of vaccination in the same way they now ask customers to check-in on the NHS Covid-19 app using QR codes.
Australian airline Qantas hit the headlines last week after it said that all those wishing to take its flights would need to be vaccinated against Covid-19.
The carrier's boss, Alan Joyce, said the move was a 'necessity' and it was likely to become a 'common thing' for airlines around the world.
He warned, during an interview with Australia's Nine Network, the airline was looking at ways to change its terms and conditions for international travellers.
He said: 'We will ask people to have a vaccination before they can get on the aircraft for international visitors coming out and people leaving (Australia) we think that's a necessity'
So all of a sudden democracy flies out the window? Defending a vaccine(s) that will never be 100% effective. Shuffle up and deal those vaccines. For a virus that can supposedly mutate as time goes by, so the longer the roll out..... To be forced on the 99.9x% that wont lose their lives through catching a virus?
Trusting the “ experts” who can’t even come up with a decent flu jab year after year. These s hite flu jabs have cost the taxpayers a fortune, with roll out and the hospital stays.
So what? And amplified by the media. Politicians lie, remember 💡
Two of them were Tories.
So nobody will be allowed to move around the world without notification of having had a jab? And you rubbish Vespas conspiracy thread?
UK's Covid vaccine minister suggests bars, cinemas and football stadiums could BAN Brits who haven't had jab as he admits No10 is looking at 'immunity passports' Baroness Dido Harding told NHS bosses her team was 'looking at' the plans They have been touted as a way to get swathes of society 'back to normal' Travel companies signalled their support, saying it could kick-start the industry
Nadhim Zahawi MP warned businesses may start requiring proof of vaccination in the same way they now ask customers to check-in on the NHS Covid-19 app using QR codes.
Australian airline Qantas hit the headlines last week after it said that all those wishing to take its flights would need to be vaccinated against Covid-19.
The carrier's boss, Alan Joyce, said the move was a 'necessity' and it was likely to become a 'common thing' for airlines around the world.
He warned, during an interview with Australia's Nine Network, the airline was looking at ways to change its terms and conditions for international travellers.
He said: 'We will ask people to have a vaccination before they can get on the aircraft for international visitors coming out and people leaving (Australia) we think that's a necessity'
More than happy for airlines, countries, stadiums, pubs, cinemas etc etc to want proof of vaccination.
Gives people the freedom of choice; those that want to get life back to some normality can take the vaccine and crack on, and those anti-vax nutjobs can choose to refuse it and face the social consequences.
Comments
Oxford University scientists published results from their second phase of testing the coronavirus vaccine, of which Britain has pre-ordered 100million doses, confirming 'positive' progress. The researchers said in a paper published in The Lancet that the jab appears to trigger a 'robust' immune system response in people of all ages and is well tolerated and safe. The team say they will be able to announce within weeks how well the vaccine, being manufactured by UK pharmaceutical firm AstraZeneca, works at protecting people from Covid-19. It comes as vaccine projects by Moderna (pictured bottom right) and Pfizer and BioNTech (bottom left) this week revealed their jabs were 94.5 and 95 per cent effective at preventing Covid-19, respectively, in large studies.
https://www.dailymail.co.uk/news/article-8735759/Oxford-coronavirus-vaccine-safe-triggers-robust-immune-response-phase-2-study-finds.html
Successful trials of Covid-19 vaccines by Moderna and a partnership between Pfizer and BioNtech have been announced.
And the Oxford coronavirus vaccine has shown an "encouraging" immune response in adults in their 60s and 70s.
Others are in development, while a third major trial - from Belgian company Janssen - is under way in the UK.
Why do we need a vaccine?
If you want your life to get back to normal, then we need a vaccine.
Even now, the vast majority of people are still vulnerable to coronavirus infection. It's only the restrictions on our lives that are preventing more people from dying.
But a vaccine would safely teach our bodies to fight the infection. It would either stop us catching coronavirus in the first place or at least make Covid less deadly.
Having a vaccine, alongside better treatments, is "the" exit strategy.
Which vaccines look most likely to succeed?
Pfizer/BioNtech is the first pharmaceutical company to share information from the final stages of vaccine testing.
The data suggests the jab could prevent more than 90% of people from getting Covid-19.
About 43,000 people have been given the vaccine, and no safety concerns have been raised.
Who will get the vaccine first and when can you have it?
Moderna ran a trial of its vaccine on 30,000 people in the US, in which half were given dummy injections,
It says its vaccine protects 94.5% of people, after only five of the first 95 trial participants who developed Covid symptoms had received the real vaccine.
Trial results from the vaccine being developed by British drug manufacturer AstraZeneca and scientists at the University of Oxford have been called "encouraging". A strong immune response was seen in adults in their 60s and 70s
The team is now staging bigger trials to see if the vaccine stops people developing Covid.
Meanwhile promising data on a Russian vaccine called Sputnik V has also been released.
Based on interim results from a phase 3 trial, the same stage reached by the Pfizer jab, Russian researchers report that it is 92% efficient.
What still needs to be done?
Trials must show the vaccine is safe
Clinical trials must show vaccines stop people getting sick or at least reduce the number who die
Huge-scale development needs to happen for the billions of potential doses
Regulators must approve the vaccine before it can be given
It is thought that 60-70% of the global population must be immune to stop the virus spreading easily (known as herd immunity) - billions of people, even if the vaccine works perfectly.
https://www.bbc.co.uk/news/health-51665497
Are you not coming out to play today?
Anti-vaxxers who spread false news about the dangers of a coronavirus cure could be
be punished by new laws to tackle misinformation.
https://www.dailymail.co.uk/news/article-8965963/Covid-anti-vaxxers-face-action-spreading-false-information-counter-terror-officer-says.html
This is an interesting idea, as you could insist on a QR code for doing just about anything, from going to work, or a pub, restaurant, using public transport, taxis, etc.
That would change a few minds.
The anti-vaxxers would soon get fed up of staying in, while everyone else was pretty much back to normal.
Which is an average of 29,000 per month.
But the real rate will be higher during the winter/ flu months.
So a vaccine may be rolled out during a period when elderly deaths will be guaranteed to be high?
I’d have thought the roll out would be better tested in a slightly younger group, that probably will see far less expected deaths.
Vaccine administered. 50 k elderly deaths in Jan. Media, was it tested for long enough, rushed through? Did the person prove positive for Covid?
Ah, no, not now. Natural causes.
The Health Secretary said in a TV briefing today that the Government has officially asked the UK drugs regulator, the MHRA, to consider licensing Pfizer's vaccine, which a report this week revealed to be 95 per cent effective at preventing Covid-19 in a clinical study. Mr Hancock said the NHS was preparing to start giving out vaccines from December but that 'the bulk' of immunisations would be done in the new year. The £15-a-dose jab, co-created by German firm BioNTech, is currently the odds-on favourite to be approved first by the MHRA, although candidates from Moderna and Oxford University are close behind. Professor Jonathan Van-Tam, deputy medical officer for England, said approval would 'happen at the speed of science'.
https://www.dailymail.co.uk/news/article-8971053/Coronavirus-vaccines-start-roll-month-Matt-Hancock-confirms.html
@chilling
Ah, finally somebody without an agenda.It’s common knowledge that there are different strains of this virus, all of which will potentially have a different affect on different individuals. This all adds up to finding a vaccine that is suitable to treat all age groups and different states of health , near impossible.
The media states the world needs billions of doses, why? Have the graveyards and crems been full of kids? 8 out of 10 that test positive have no symptoms, as their immune system have won the battle before it even started.
You look at the worldometer charts, which can be confusing, but not when you search for the health stats and care systems for individual countries.
It’s not just the “ standard” vulnerable that get hit. Some of those countries have bad diets and heavy drinkers to blame for their counts. Russia, Poland, Ukraine etc.
I would focus more on the health aspect than a vaccine, prevention.
So back to the vaccine.
The elderly are the ones that are the coming off worse, by far.It’s also common knowledge that the elderly can easily get pneumonia after influenza. So why are big Pharma looking for a magic bullet for this virus, when the annual flu jab has about a 50% success rate? Who is responsible for the deaths in previous years for a poor performing vaccine?
There are obviously going to be several vaccines, so who decides which one to go with?
Nobody will know if they are any good for a couple of years imo.
So when you look back, how many lives are going to be saved? Answer. You won’t know.
If you believe the numbers ( which I don’t) this virus is still sitting very low on the causes of death this year.
Something needs to change regarding the elderly populations health imo.
Better diets, more exercise where possible. Spend money and research on that.
I’ve worked in several care homes over the years. Same old routine,get them washed and dressed, then fed, then sit them down for hours on end. No wonder their immune systems are poor.( not as a care worker)
Trying to find ways to improve the immune system of the elderly in the future is more important than vaccines imo.
Let’s see if all the pneumonia and influenza cases get mixed together with the Covid numbers this winter. I can answer that, you won’t know.
So all in all,you won’t know what small % are saved by a vaccine(s) to fight another day.
“ A good thing”? You won’t know.
In fact, with so many elderly having so many different illnesses,you won’t even know if it was the vaccine that killed them.
If it’s a bad winter for flu,then you won’t be able to make head nor tail of any of the numbers.
Trials for AstraZeneca's new 'antibody cocktail' treatment will begin in the UK - and it could prevent Covid-19 for up to a YEAR
Manchester participant will be the first in the world to receive 'antibody cocktail'
Clinical trial will recruit 5,000 people, including 1,000 from nine sites in the UK
Government has signed a deal to secure one million doses if the trial is a success
Kate Bingham, chairwoman of the UK's Vaccine Taskforce, said: 'This is part of the portfolio to protect the whole UK.
'So, obviously, vaccines work in people who have a functional immune system.
'[But] if you are immuno-suppressed and you are going through bone marrow transplants, or indications or treatments that actually reduce your ability to mount an immune response, then this is basically the only current way of providing that short-term passive immunity.
'So we are absolutely looking to protect those people who are immuno-suppressed or those people who need immediate protection, because you will remember that vaccines typically take about six weeks to work.'
https://www.dailymail.co.uk/news/article-8972013/Trials-AstraZeneca-s-new-Covid-19-antibody-treatment-set-begin-UK.html
Professor KAROL SIKORA celebrates positive coronavirus vaccine news from Pfizer, Moderna and AstraZeneca, saying the 'whole Covid landscape has been
transformed.'
https://www.dailymail.co.uk/debate/article-8979717/Professor-KAROL-SIKORA-says-coronavirus-vaccines-really-game-changers.html
PROF BRENDAN WREN: Once an immunisation programme is fully under way early next year, society really can begin to return to normal, thanks to the work of scientists across the globe.
https://www.dailymail.co.uk/debate/article-8984017/PROF-BRENDAN-WREN-fear-Covid-vaccine.html
Baroness Dido Harding told NHS bosses her team was 'looking at' the plans
They have been touted as a way to get swathes of society 'back to normal'
Travel companies signalled their support, saying it could kick-start the industry
Nadhim Zahawi MP warned businesses may start requiring proof of vaccination in the same way they now ask customers to check-in on the NHS Covid-19 app using QR
codes.
Australian airline Qantas hit the headlines last week after it said that all those wishing to take its flights would need to be vaccinated against Covid-19.
The carrier's boss, Alan Joyce, said the move was a 'necessity' and it was likely to become a 'common thing' for airlines around the world.
He warned, during an interview with Australia's Nine Network, the airline was looking at ways to change its terms and conditions for international travellers.
He said: 'We will ask people to have a vaccination before they can get on the aircraft for international visitors coming out and people leaving (Australia) we think that's a necessity'
https://www.dailymail.co.uk/news/article-9000479/Test-Trace-working-making-immunity-passports.html
Defending a vaccine(s) that will never be 100% effective.
Shuffle up and deal those vaccines.
For a virus that can supposedly mutate as time goes by, so the longer the roll out.....
To be forced on the 99.9x% that wont lose their lives through catching a virus?
Trusting the “ experts” who can’t even come up with a decent flu jab year after year.
These s hite flu jabs have cost the taxpayers a fortune, with roll out and the hospital stays.
More than happy for airlines, countries, stadiums, pubs, cinemas etc etc to want proof of vaccination.
Gives people the freedom of choice; those that want to get life back to some normality can take the vaccine and crack on, and those anti-vax nutjobs can choose to refuse it and face the social consequences.